need some clarity in the documentation

["Sean" <smcmahon@xxxxxxxxxxx>]

Could any one tell me what this means
Interactive PREFIX arg says to set the rate globally.
This line on the online manual is common for anything dealing with setting
synth options globally.  How do you set synth options such as punctuation,
rate, voice pitch so they'll be set the next time you login or for good in
the curent session?  thanks
Sean

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